What is true about the end products of glycolysis?\

Question

Professor PC Thomas Classes · Answer

(a) : In glycolysis, two molecules of ATP are consumed during two phosphorylation reactions to form fructose 1, 6-bisphosphate. In return, four molecules of ATP are produced by substrate level phosphorylation (conversion of 1, 3-bisphosphoglycerate to 3-phosphoglycerate and phosphoenol pyruvate to pyruvate). Two molecules of $\mathrm{NADH}_{2}$ are formed at the time of oxidation of glyceraldehyde 3-phosphate to 1, 3-bisphosphoglycerate. The net reaction of glycolysis is as follows: $$ \begin{aligned} 	ext { Glucose }+2 \mathrm{NAD}^{+}+2 \mathrm{ADP}+ & 2 \mathrm{H}_{3} \mathrm{PO}_{4} ightarrow \ 2 & 	ext { Pyruvate }+2 \mathrm{NADH}+2 \mathrm{H}^{+}+2 \mathrm{ATP} \end{aligned} $$ Each NADH is equivalent to 3 ATP, so the net gain in glycolysis is 8 ATP.\