Assertion : During organ transplantation if patient is not provided with cyclosporin A , he/she may

Question

Assertion : During organ transplantation if patient is not provided with cyclosporin A , he/she may reject the transplanted organ.\ Reason : Cyclosporin A produced by fungus Trichoderma polysporum act as immunosuppressive agent.\

Professor PC Thomas Classes · Answer

(a) : Cyclosporin A is cyclic oligopeptide obtained through fermentative activity of fungus Trichoderma polysporum. It has immunosuppressive properties and inhibits activation of T-cells. T- cells of immune system mainly function to kill non-self cells. Because cyclosporin A inhibits T-cell function, it causes immunosuppression and chances of rejection of transplanted organ are reduced. Thus, organ transplant patients are provided with cyclosporin A.